Classification of Patellofemoral Pain

image In 1998, one of the most influential publications of the last 2 decades was published on treatment of the patellofemoral joint.  Four of the leaders and pioneers of sports medicine and orthopedic rehabilitation – Kevin Wilk, George Davies, Bob Mangine, and Terry Malone – teamed up to develop a classification system for the differential diagnosis of patellofemoral pathologies.  This manuscript was the first to offer treatment strategies based on specific diagnoses for patellofemoral pain.  Today, this manuscript still holds extreme value and if you haven’t read it, I highly recommend finding a copy.

By far the most critical component of treating the patellofemoral joint is an accurate diagnosis.  I will always challenge me students in this regard – find the cause of their symptoms and STOP using “patellofemoral pain” as a diagnosis.  At first this can seem like a daunting task as the true source of patellofemoral pain can be misleading.  However, using a classification system to group types of diagnoses can be extremely helpful in the formation of your treatment program.

The following is part 3 of the series on solving the patellofemoral mystery:

Differential Diagnosis of Patellofemoral Pain

Patellar Compression Syndromes

Patellar compressive syndromes are described as pathologies involving excessive compression between the patella and the trochlea due to tight surround soft tissue.  These can result in significant changes to the articular surfaces of the patella and trochlea over time.  This can be broken down into two distinct types of compression syndromes:

  •  Excessive lateral pressure syndrome (ELPS).  ELPS was originally described as occurring when the patella is overconstrained by soft tissue tightness, specifically timagehe lateral retinacular tissue.  The patient will exhibit a lateral tilted and/or shifted patella and decreased medial glide.  There is often times medial discomfort as the medial retinacular tissue is stretched due to a laterally displaced patella.  I often find palpating the medial patellofemoral ligament elicits a decent amount of discomfort.  I believe proximal and distal influences in the kinetic chain also effect the alignment of the patellofemoral joint and can cause an ELPS-like syndrome, though through a different mechanism.  This should be assessed and is discussed more below.
  •  Global patellar pressure syndrome (GPPS).  GPPS occurs when there is a general and diffuse medial and lateral soft tissue tightness that reimagesults in the patella being excessively compressed within the throclea.  This is more commonly see after direct trauma, immobilization due to fracture, or knee surgery with the development of arthrofibrosis.  Have you ever had a patient lose patella mobility after an ACL reconstruction?  This is a good example of GPPS.  These patients may also have decreased superior patellar mobility as the knee is immobilized in flexion.

Patellar Instability

image On the other side of the spectrum is patellar instability, which can range from an acute dislocation to recurrent instability.  On examination, patients will have excessive patellar mobility laterally.  This is often associated with a shallow trochlea, so many patients may be predisposed to this condition.  I would suspect this with the patient with chronic subluxations.  Also, acute episodes of subluxation or dislocation may result in rupture of the imagemedial patellofemoral ligament and subsequent medial pain.  Patients with chronic subluxation usually don’t have as much sensitivity medially as their tissue adapts and/or tears over time.

Try this – perform patellar imagegliding at 0 degrees of flexion and then again at ~30 degrees of flexion.  If the patella continues to have excessive gliding at 30 degrees, then they likely have a shallow trochlea and poor static stability.  These patients are challenging to treat as the static stability is a primary cause of their symptoms.

Biomechanical Dysfunction

The knee appears to take a good amount of stress when biomechanical faults are present both proximally and distally within the kinetic chain.  Alterations in foot and ankle mechanics, hip strength, leg length discrepancy, flexibility deficiencies, and any combination of these factors can have a negative impact on the forces observed at the patellofemoral joint.  Not only can biomechanical dysfunction lead to increased stress, it can also lead to chronic adaptations over time.  Take for example someone with weak hip external rotation.  This could lead to a dynamic inability to control the hip adduction and IR moment at the knee and cause the femur to rotate into internal rotation during activities.  This will cause the patella shift laterally and can cause articular cartilage and soft tissue changes that will mimic a typical ELPS patient.  You can loosen up the lateral soft tissue but without treating the true cause, the hip weakness, symptoms will continue to occur.

This will be discussed in greater detail in a future post in this series as this is an important factor to consider.

Direct Patellar Trauma

image This is my least favorite pathology as I seem to always be a victim of direct patellar trauma myself.  Have you ever hit your knee against a table leg?  Every time I do, and it seems frequent, I think of the acute trauma my articular cartilage just took!  This is also seen with patients falling on their knee, which is common up here in the northeast during the winter when it gets icy.  Subjective exam should lead you this way, but you may have to probe, sometimes patients will forget that they fell 3 weeks ago or not correlate their symptoms with the incident.

Patients in this classification can include bone bruises, articular cartilage lesions, and even fractures.

Soft Tissue Lesions

There are a few common soft tissue lesions that can occur to the patellofemoral joint.  Accurate diagnosis of these syndromes usually involves direct palpation to these areas and a certain mechanism of trauma to the area.

  • image Suprapatellar plica syndrome.  The plica is an interesting and debatable structure.  I have always been of the belief that plica is very individual and some people have larger synovial folds than others.  Most common is the suprapatellar plica, which is located medial and superior to the patella.  This structure gets tight against the femoral condyle as the knee flexes so repetitive activities such as bike riding can cause this.
  • IT band friction.  Similarly, ITB friction can occur laterally as the patellar tract of the IT band gets taught against the lateral femoral condyle during flexion.
  • Fat pad syndrome.  The fat pad of the knee is highly vascularized and has rich imagenerve fibers.  When a patients falls on their knee, they may inflame this structure.  You can easily palpate on either side of the patellar tendon and find discomfort.  Be sure to assure that you are not palpating the patellar tendon as treatment for this will vary.
  • Medial patellofemoral ligament injury.  This was previously discussed above, but realize that any issues with chronic ELPS or patellar instability will cause MPF ligament pathology.

Overuse Syndromes

imageOveruse syndromes include patellar tendonitis and less commonly quadriceps tendonitis superiorly.  Patellar tendonitis most commonly occurs at the inferior pole of the patella, but may also occur mid-tendon or at the tibial tuberosity.  Patients will  present with typical symptoms of a tedonopathy.

Two types of apophysitis can occur in the knee.  These are common in adolescents during growth spurts and in athletes participating in jumping sports.  These can easily be palpated and may be seen I’m not a big fan of naming things after people as they don’t offer any description of what the pathology is so I will use two versions of the terminology.

  • Traction apophysitis of the tibial tuberosity (Osgood-Schlatter).
  • Traction apophysitis of the inferior patellar pole (Sindig-Larsen-Johansson).

As you can see, there are many different pathologies that can occur to the patellofemoral joint.  The above list is not intended to be all-encompassing, but rather to create categories of diagnoses that share similar treatment guidelines.  There are other potential source of PF issues, including neurologic origins from the lumbar spine or reflex sympathetic dystrophy, however I wanted to keep this discussion orthopedic.  Once I rule out orthopedic issues I will explore other origins and a likely referral back to the doctor or specialist.

To vaguely classify each patient as “patellofemoral pain syndrome” would be doing a disservice to the patient and will likely not result in optimal outcomes.  A clear and accurate differential diagnosis is by far the most important aspect of treating the patellofemoral joint.

Next time a patient comes to you with a referral stating “PFPS” or “anterior knee pain,” I challenge you to attempt to classify the patient appropriately.  Treatments will vary greatly for each diagnosis.  These will be discussed in a future post.

Continue on to Part 4: The 10 Principles of Patellofemoral Rehabilitation

Wilk KE, Davies GJ, Mangine RE, Malone TR. (1998). Patellofemoral disorders: a classification system and clinical guidelines for nonoperative rehabilitation. JOSPT DOI: 9809279

11 replies
  1. Raymond
    Raymond says:

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  3. ata
    ata says:

    Dear Mike
    I have a 30 years old patient who rides bicycle with pain located on the inferior third of the patella and it is sensitive to pressure however there is no pain in the medial or lateral border of patella and it seems just the center is irriated, the patellar tendon seems ok and I reject patellar tendonitis, also no sign of artritis in the x ray,would you please help me

  4. Mike Reinold
    Mike Reinold says:

    Aaron, thanks for the comments. Sounds like you have very common symptoms from your patients. See how PF pain can be so frustrating? You are probably right, to an extent, with your retinacular concept. Remember that patients with lateral tracking have chronic stretching of the medial retinaculum. This causes the discomfort. You should rule out that they do not have a specific MPFL injury, palpation usually works well. As I mention in this series, your job is to find why they are tracking that way.

    You are not going to get these patients better in a couple of weeks, hang in there and think out side the box (or at least outside the knee!). Good luck.

  5. Aaron
    Aaron says:

    First I just want to say thank you. As a PT student this website has really been a great source for accelerating my education. The evidence-based rationale is extremely helpful.

    My question to any PT's out there is about the anteromedial knee. In my affiliation this summer it seems like all my knee patients have the SAME anteromedial knee pain between the MCL and patellar tendon. I usually give them the explanation that its the stretching of the medial retinaculum, but I was curious as if there's anything else it could be.

    The only differential diagnosis for this medial knee pain I could come up with are: mediopatellar femoral ligament/medial retinaculum stretching and anteromedial meniscus pain. And all these patients seem to have very weak quadriceps strength. Are there any other structures or pathologies I should be looking for?

    Any kind of feedback would help.

  6. Mike Reinold
    Mike Reinold says:

    Susan, would love to hear your 5 exercises. Would you be interested in email me and maybe submitting a guest post? If not, how about at least just listing them here in the comments? Thanks for the comments,

  7. Susan Peterson
    Susan Peterson says:

    I love this post. We get a ton of kids, mainly adolescent girls, who have been through countless doctor's appts,PT's and even surgical procedures. Most of them fit the patellar instability/biomechanical category. There are so many therapists out there that are stuck in the "strengthen the VMO and stretch the ITB" line of thinking. Patellar pain is definitely one of those problems where looking at the proximal/distal joints is a necessary part of the exam. A lot of these kids deal with this for so long they start feeling like their parents, doctor's, and therapists don't believe they have pain. I have 5 basic hip ex's that I give most of these pt's. Can't wait to hear more from you

  8. Mike Reinold
    Mike Reinold says:

    Tough to say without more info. Would definitely suggest sending for a second opinon from an orthopedist.

  9. Anonymous
    Anonymous says:

    have a patient with severe PT tendon pain, cant fully extend knee, hesitatnt to flex but can. MD says tight lat ret., not responding to any modalities, stretching, etc. Any suggestions?

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